Job Offer

Scientific Officer – New Approach Methods

Application Open Date: 
22/07/2019 - 02:01
Deadline Date: 
26/08/2019 - 13:00
Helsinki, Finland
Type of Contract: 
Temporary staff
JOB Description: 
The Scientific Officer will work in the Directorate for Prioritisation and Integration of the Agency, in the Computational Assessment Unit. The Unit develops computational methods and tools for collecting, analysing and making available data on chemicals. The tools developed by the Unit help the Agency with prioritisation and selection of dossiers and substances for further regulatory actions, such as compliance checks. The Unit promotes and uses alternative test methods, including integrated testing strategies, QSAR, in-vitro assays, read-across, categories and other New Approach Methods (NAM). The Unit is responsible for IUCLID – the tool used by companies and authorities worldwide for creating and exchanging chemical data. The Unit’s international work includes co-managing the QSAR Toolbox development with OECD and the coordination of the APCRA work together with the United States’ Environmental Protection Agency (US EPA) and Health Canada. The Scientific Officer will contribute to the successful implementation of the Unit’s tasks. The work will consist of the following: QSAR related activities: • Execute QSAR expert consultations: expert consultations involve the running of predictive toxicology tools, answering specific questions arising from assessments of human health or environmental endpoints; • Support the ECHA Grouping Strategy, specifically in assisting the assessment of all available information, including generating predictions where relevant; • Maintain the knowledge base of QSAR models and approaches; • Contribute to the development of the OECD QSAR Toolbox; • Contribute to the development of guidance/manuals for QSAR approaches and/or OECD QSAR Toolbox; • Support ECHA’s Scientific Data Analysis Platform (SDAP) with predictions on large groups of chemicals and constituents. New Approach Methods related activities: • Contribute to the New Approach Methods (NAM) projects ECHA is undertaking/contributing to; • Analyse multi-omics (mainly transcriptomic and metabolomics) datasets from toxicological studies; • Analyse data generated by ToxCast and Tox21 programmes. General activities: • Contribute to the REACH Article 117.3 report; • Other activities in support of alternative methods as appropriate.
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